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Dataset Description
  • Dataset Name: HuGE Navigator
  • Species: Human
  • Method: Literature data mining
  • No. of Genes: 188
  • Phenotype: Alcoholism
  • Publication: Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
  • Dataset Summary: HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

    Gene list of this dataset (188 genes)
    Page: 1 2 3 4 list all   
    GeneIDSymbolNameGenetic locationPhenotypeNo. of Support Publications
    1394CRHR1corticotropin releasing hormone receptor 117q12-q22Alcoholism3
    1493CTLA4cytotoxic T-lymphocyte-associated protein 42q33Alcoholism2
    1585CYP11B2cytochrome P450, family 11, subfamily B, polypeptide 28q21-q22Alcoholism1
    1588CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 115q21.1Alcoholism1
    1543CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 115q22-q24Alcoholism2
    1571CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 110q24.3-qterAlcoholism24
    1621DBHdopamine beta-hydroxylase (dopamine beta-monooxygenase)9q34Alcoholism5
    27185DISC1disrupted in schizophrenia 11q42.1Alcoholism2
    1743DLSTdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)14q24.3Alcoholism1
    1812DRD1dopamine receptor D15q35.1Alcoholism4
    1813DRD2dopamine receptor D211q23Alcoholism58
    1814DRD3dopamine receptor D33q13.3Alcoholism9
    1815DRD4dopamine receptor D411p15.5Alcoholism8
    1816DRD5dopamine receptor D54p16.1Alcoholism1
    2047EPHB1EPH receptor B13q21-q23Alcoholism1
    2099ESR1estrogen receptor 16q25.1Alcoholism1
    2166FAAHfatty acid amide hydrolase1p35-p34Alcoholism2
    2534FYNFYN oncogene related to SRC, FGR, YES6q21Alcoholism2
    2550GABBR1gamma-aminobutyric acid (GABA) B receptor, 16p21.31Alcoholism1
    2554GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 15q34-q35Alcoholism8
    2555GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 24p12Alcoholism12
    2556GABRA3gamma-aminobutyric acid (GABA) A receptor, alpha 3Xq28Alcoholism1
    2558GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 515q11.2-q12Alcoholism1
    2559GABRA6gamma-aminobutyric acid (GABA) A receptor, alpha 65q34Alcoholism8
    2560GABRB1gamma-aminobutyric acid (GABA) A receptor, beta 14p12Alcoholism3
    2561GABRB2gamma-aminobutyric acid (GABA) A receptor, beta 25q34Alcoholism5
    2562GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 315q11.2-q12Alcoholism5
    2566GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 25q31.1-q33.1Alcoholism4
    2571GAD1glutamate decarboxylase 1 (brain, 67kDa)2q31Alcoholism1
    2572GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)10p11.23Alcoholism1
    51083GALgalanin prepropeptide11q13.2Alcoholism2
    2587GALR1galanin receptor 118q23Alcoholism1
    8811GALR2galanin receptor 217q25.3Alcoholism1
    8484GALR3galanin receptor 322q13.1Alcoholism1
    2784GNB3guanine nucleotide binding protein (G protein), beta polypeptide 312p13Alcoholism1
    2890GRIA1glutamate receptor, ionotropic, AMPA 15q33|5q31.1Alcoholism1
    2899GRIK3glutamate receptor, ionotropic, kainate 31p34-p33Alcoholism2
    2902GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 19q34.3Alcoholism2
    2904GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B12p12Alcoholism6
    2905GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C17q25Alcoholism1
    2906GRIN2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2D19q13.1-qterAlcoholism1
    2917GRM7glutamate receptor, metabotropic 73p26.1-p25.1Alcoholism1
    2918GRM8glutamate receptor, metabotropic 87q31.3-q32.1Alcoholism1
    2938GSTA1glutathione S-transferase A16p12.1Alcoholism1
    2944GSTM1glutathione S-transferase M11p13.3Alcoholism6
    2947GSTM3glutathione S-transferase M3 (brain)1p13.3Alcoholism1
    2950GSTP1glutathione S-transferase pi11q13Alcoholism4
    2952GSTT1glutathione S-transferase theta 122q11.23Alcoholism3
    3077HFEhemochromatosis6p21.3Alcoholism2
    3105HLA-Amajor histocompatibility complex, class I, A6p21.3Alcoholism1
    Page: 1 2 3 4 list all